MSCI Nihonkabu ESG Select Leaders Index
ONO has been selected as the MSCI Nihonkabu ESG Select Leaders Index developed by the U.S. Inc., MSCI. (As of July 2026)
This index is composed of Japanese companies that excel in ESG assessment by industry among the stocks that make up the MSCI Nihonkabu IMI Index. As of November 2025, a total of 461 companies were selected.

FTSE4Good Index Series
ONO has been selected as the FTSE4Good Index Series for the consecutive years since 2018. (As of July 2026)
This index is designed by FTSE Russell, a member of the London Stock Exchange group. Companies with relatively good environmental, social and governance practices are selected in each sector.
https://www.lseg.com/en/ftse-russell/indices/ftse4good

FTSE JPX Blossom Japan Index*
ONO has been selected for the FTSE JPX Blossom Japan Index since 2018. (As of July 2026)
This index is designed by FTSE Russell, a member of the London Stock Exchange group. Japanese companies with relatively good environmental, social and governance practices are selected in each sector.
https://www.lseg.com/en/ftse-russell/indices/blossom-japan

FTSE JPX Blossom Japan Sector Relative Index*
ONO has been selected for the FTSE JPX Blossom Japan Sector Relative Index since 2022. (As of July 2026)
The index is designed by FTSE Russell, a member of the London Stock Exchange group.
Japanese companies with relatively good environmental, social and governance practices are selected in each sector.
The Index is designed as a sector neutral benchmark and supports climate transitions to a low carbon economy, especially for those companies with particularly high GHG emissions, by evaluating companies’ climate governance and climate change efforts via the Transition Pathway Initiative’s Management Quality Score.
https://www.lseg.com/en/ftse-russell/indices/blossom-japan

S&P/JPX Carbon Efficient Index
ONO has been selected as a constituent of the “S&P/JPX Carbon Efficient Index” for the consecutive years since 2018. (As of March 2026)
This index comprises companies included in the Tokyo Stock Price Index (TOPIX), and the weight of constituent is determined by the disclosure status of environmental information and carbon efficiency (Carbon emissions per unit of revenue) based on market capitalization.

Dow Jones Best-in-Class Indices
ONO has been selected as a component of the Dow Jones Best-in-Class Asia Pacific Index for consecutive years since 2020. (As of April 2026)
The Dow Jones Best-in-Class Indices is a sustainability stock index published annually by S&P Dow Jones Indices in the U.S., analyzing corporate activities in terms of the three aspects of economy, environment, and society, and selecting index components.
CDP [Climate Change] [Water Security]
ONO has been selected by CDP, a global environmental non-profit organization, as the highest A-List company in the two categories of [Climate Change] and [Water Security], being recognized our commitment and disclosure to climate change and water security for the consecutive years since 2021.

CDP [Supplier Engagement Assessment]
ONO has been selected by CDP, a global environmental non-profit organization, as the highest rating of [Supplier Engagement Assessment leader] in Supplier Engagement Assessment since 2024.
This assessment evaluates how effectively companies are working with suppliers to address climate change issues.

KENKO Investment for Health and Outstanding Organizations of KENKO Investment for Health – White 500
In March 2026, we were selected as a “2026 KENKO Investment for Health” as a company that considers the health management of employees from a managerial perspective and as a company that is strategically engaged in health management. This marks the third time that Ono Pharmaceutical has been selected for this designation, which is jointly awarded by the Ministry of Economy, Trade and Industry (METI) and the Tokyo Stock Exchange (TSE). In addition, we have been accredited for eight consecutive years in the “2026 Outstanding Organizations of KENKO Investment for Health (White 500 / Large Enterprise Category),” which is jointly implemented by METI and the Nippon Kenko Kaigi*.
Moving forward, we will continue to engage in health management through a variety of activities.
NIKKEI Sustainable Management Survey, Smart Work Edition
ONO was rated 4 stars in the NIKKEI Sustainable Management Survey, Smart Work Edition 2025.
NIKKEI Sustainable Management Survey, Smart Work Edition has been conducted by Nikkei Inc. since 2017, targeting listed companies and leading unlisted companies across Japan. "Smart Work Management" is a management strategy that aims to maximize the utilization of human resources and accelerate investment in human capital to foster innovation, improve productivity, and maximize corporate value.
Companies are evaluated on a 5-star scale based on their implementation of "Smart Work Management," specifically focusing on three elements: human resource utilization, human resource investment, and the use of technology.

NIKKEI Sustainable Management Survey, SDGs Edition
ONO was rated 4 stars in the NIKKEI Sustainable Management Survey, SDGs Edition 2025.
NIKKEI Sustainable Management Survey, SDGs Edition has been conducted by Nikkei Inc. since 2019, targeting listed companies and leading unlisted companies across Japan. Companies are evaluated on a 5-star scale based on their efforts to address social, economic, and environmental issues through their business and to enhance their corporate value in the four areas: SDG Strategy and Economic Value, Social Value, Environmental Value, and Governance.

SOMPO Sustainability Index
Ono has been selected for the SOMPO Sustainability Index for consecutive years since 2022. (As of June 2026)
"Sompo Sustainability Index" is an active index composed of approximately 300 stocks with superior ESG evaluations. It is constructed by integrating stock selection based on ESG evaluations by Sompo Risk Management with stock valuation by Sompo Asset Management.
